Once weekly cagrilintide for weight management in people with overweight and obesity: a multicentre, randomised, double blind, placebo controlled and active controlled, dose finding phase 2 trial The Lancet In the REDEFINE 1 phase 3a trial, semaglutide at a dose of 2.4 mg with cagrilintide at a dose of 2.4 mg led to significant body weight reduction in adults without diabetes and Current Strategies in Managing Obesity STRIVE Obesity Cagrilintide & Semaglutide in Overweight Adults (REDEFINE 1) NEJM Med Journal Club YouTube
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coadministered cagrilintide and semaglutide in adults with overweight or obesity In the REDEFINE 2 phase 3a trial involving adults with obesity and diabetes, the use of cagrilintide–semaglutide resulted in a significantly lower body weight than placebo at 68 weeks. Full trial results