lipid peroxide accumulation is mainly by absence, or insufficient activity, of selenium peroxidase glutathione peroxidase 4 (GPX4) New research targeting senescent zombie" cells highlights potential #cancer therapies reducing inflammation, tumor growth, and treatment related damage through Glutathione Peroxidase 4 (GPX4) inhibition. . Article Glutathione peroxidase 1 and neuromodulation: Novel potentials of an old enzyme ScienceDirect Design, synthesis, and biological evaluation of nitroisoxazole containing spiro[pyrrolidin oxindole] derivatives as novel glutathione peroxidase 4 mouse double minute 2 dual inhibitors that inhibit breast adenocarcinoma cell proliferation ScienceDirect