The Electron Transport Chain and Pentose Phosphate Pathway biochemistry Pentose Phosphate Pathway made simple. This pathway has two major jobs: Generate NADPH Produce ribose 5 phosphate NADPH protects cells from oxidative stress and supports fatty acid, cholesterol, steroid, nitric oxide, and respiratory burst The Electron Transport Chain and Pentose Phosphate Pathway biochemistry Pentose Phosphate Pathway: High Yield Biochemistry Notes Oncourse