G6PD Deficiency Causes Haemolytic Anaemia Glucose 6 phosphate dehydrogenase is an enzyme in the hexose monophosphate shunt that synthesizes NADPH. The NADPH is used to convert oxidized glutathione (GSSG) to reduced glutathione ( Is Glutathione Safe for G6PD Deficiency? Understanding the Antioxidant Connection Cymbiotika CYMBIOTIKA Loss of glucose 6 phosphate dehydrogenase function increases oxidative stress and glutaminolysis in metastasizing melanoma cells PNAS Glucose 6 Phosphate Dehydrogenase Deficiency Symptoms, Pathophysiology, Diagnosis and Treatment